Coffee (decaf and decaffeinated) contains mu opioid receptor antagonists

[230gr]

Coffee (decaf and decaffeinated) contains mu opioid receptor antagonists

This might be of some use to people trying to get off opioids. 

Coffee (decaf and decaffeinated) contains compounds such as 4-Caffeoyl-1, 5-quinide (AKA 4-Caffeoylquinide or 4-CQL) which have a high affinity for the mu opioid receptor. These mu opioid receptor antagonists compounds are unrelated to caffeine.




These compounds do not activate the receptor but they prevent it being occupied and activated by endogenous opioids (produced naturally by the body) or by exogenous opioids, such as morphine.


See:
“Problems arising from coffee due to opioid receptor antagonists and caffeine”

http://aminotheory.com/coffee/